Hey Ben, I am glad the mj is helping. And I am sorry about the wife. My hubby feels much the way she does. It took about 8 yrs for me to make any headway and convince him differently. He still isn't 100%, but it is getting a little better. He also doesn't know how often and how much I use.
Maybe you could try showing her all the side effects those medications can have. If she approves and lets you smoke, will you be discontinuing the medications?
I too have some depression/anxiety issues and I find the mj helps. I am slowly weaning myself from my med, celexa.
Good luck.