I should add that most people decarb before extracting the cannabinoids for edibles. I believe my slow cooker method of making cannabutter decarbs during the 12+ hours of simmering though I have no scientific data to support my belief. I do have anecdotal evidence that the slow cooking does decarb since I just made a batch of butter that I tried a bit too much of(it tasted horrible)and I got plowed under. My brownies, which I always assumed decarbing was taking place by cooking the batch at 300 deg F for about an hour, never fail to get me as baked as the brownies. If you plan on making tincture and not cooking with it, I would recommend decarbing the trim.