Hey WWM, sure you can take some healthy 4 inch cuttings from the lower branches. Don't go nuts and take 200 of em. If you take a few, do as ozzydiodude says and root them under 24/7 low lighting, (a 150 watt HPS at 8 to 12 inches will work fine), with only 3 or 4 leaves per/cutting. Use a quality rooting hormone. You'll of course have to move them out of your flowering room to gain 24/7 light.
Now "Here's the rest of the story" as Paul Harvey used to say; the reaction to being taken while the host plant is in flowering is dependant on strain, the health of the plant, the quality of your rooting hormone and the handling of your cuttings.
If you prepare a glass of neutral ph water with the proper mix of rooting hormone in the water and make your cuts with a very sharp razor at a nice 45 degree angle, IMMEDIATELY put the cutting in the water/hormone and THEN re-cut it right away with another clean, 45 degree cut while under the water, then you'll have your best chance at successful clones.
There is a chance that the clones will hermi on you. Some strains just don't like cloning and if cloned during advanced flowering, some turn hermie.
Yes, I've done it with hundreds of clones. Everything from dirt weed to world class white strains. Some work, others don't.
The only way you'll know if yours will work is to do some.
Good luck my friend!