You're never going to match the efficiency and capacity of an inline exhaust that has internal impellers designed to really suck out air. The choices are between a rugged inline fan to build a simple exhaust, and a combination of air conditioning and/Or dehumidifier (depending on how much heat you're dealing with and whether the A.C. can drop out as much humidity as you need it to) plus CO2 enrichment to do a sealed room setup. These are both valid approaches to your challenge, and you'll still use the clip on fans for internal circulation.