burnin1
Well-Known Member
From metro.co.uk
Scientists know how to switch off weed side-effects like paranoia
Ollie McAteer for Metro.co.ukFriday 10 Jul 2015 3:40 pm
This is good news (Picture: REX)
Research has led to experts identifying two different mechanisms that control the medical effects and psychological effects.
This is an important break-through because cannabis has been proven to slow tumour growth in mice in a recent study.
Peter McCormick, from the University of East Anglia, said: There has been a great deal of medical interest in understanding the molecular mechanisms at work in THC, so that the beneficial effects can be harnessed without the side-effects.
THC acts through a family of cell receptors called cannabinoid receptors. Our previous research revealed which of these receptors are responsible for the anti-tumour effects of THC. This new research demonstrates how some of the drugs beneficial effects can be separated from its unwanted side effects.
During the research scientists found out that psychological side-effects of the drug, such as memory defects, mood swings, anxiety, and paranoia, were triggered by a single pathway in the brain that was separate from the pathway that triggers the drugs cancer-killing properties.
Two types of cells exist in this pathway positioned close together. The team blocked the activity of one cell a type of serotonin receptor in mice.
They were put through a series of experiments testing memory, mood and pain.
When they isolated just one cell they found differences in memory and mood tests but not pain.
Read more: http://metro.co.uk/2015/07/10/scien...-effects-like-paranoia-5289645/#ixzz3fbM1Bmj6
Scientists know how to switch off weed side-effects like paranoia
Ollie McAteer for Metro.co.ukFriday 10 Jul 2015 3:40 pm
This is good news (Picture: REX)
Research has led to experts identifying two different mechanisms that control the medical effects and psychological effects.
This is an important break-through because cannabis has been proven to slow tumour growth in mice in a recent study.
Peter McCormick, from the University of East Anglia, said: There has been a great deal of medical interest in understanding the molecular mechanisms at work in THC, so that the beneficial effects can be harnessed without the side-effects.
THC acts through a family of cell receptors called cannabinoid receptors. Our previous research revealed which of these receptors are responsible for the anti-tumour effects of THC. This new research demonstrates how some of the drugs beneficial effects can be separated from its unwanted side effects.
During the research scientists found out that psychological side-effects of the drug, such as memory defects, mood swings, anxiety, and paranoia, were triggered by a single pathway in the brain that was separate from the pathway that triggers the drugs cancer-killing properties.
Two types of cells exist in this pathway positioned close together. The team blocked the activity of one cell a type of serotonin receptor in mice.
They were put through a series of experiments testing memory, mood and pain.
When they isolated just one cell they found differences in memory and mood tests but not pain.
Read more: http://metro.co.uk/2015/07/10/scien...-effects-like-paranoia-5289645/#ixzz3fbM1Bmj6
