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From hightimes.com
Research: CBD Helps Alzheimers Disease
By Sirius J · Mon Aug 03, 2015
Past research has implicated CBD in the treatment of Alzheimers disease because of its antioxidant, anti-inflammatory and neuroprotective effects, but due to the irreversible nature of the diseases progression, real breakthroughs are hard to make. For the first time ever, scientists in Australia looked at what long-term oral CBD administration does, and found that it improves social recognition in mice with Alzheimers.
One of the most dramatic and disturbing symptoms of Alzheimers disease is the loss of social recognition; many patients fail to recognize even their own children. Seemingly irreversible changes happen in the brain when a person gets Alzheimers, making treatment of the disease very difficult.
CBD had previously been shown to offer some help as a neural antioxidant in preclinical trials on mice, but without real improvement in their mental state. By using special transgenic mice breed to succumb to the disease, scientists were able to analyze the effects of what preventative CBD treatment does, and the results were impressive. Mice that took 20 mg/kg of CBD (equivalent to almost a gram and a half for someone of average weight) every day before showing symptoms of Alzheimers didnt develop social recognition deficits, even in the middle of full-fledged Alzheimers disease. While some other symptoms were still present, the mice generally had better cognition if they took CBD for long periods of time. The scientists think that this prevention may be linked to CBD-induced retention of dietary phytosterols or neuroinflammatory processes in the brain of mice with the disease.
With daily progress in genomic research, so-called personalized medicine will allow doctors to preventatively treat diseases before they even happen. Mutations on certain chromosomes can whether or not a person is at risk for developing Alzheimers; CBD may one day be used to help these people lead a better life.
http://www.hightimes.com/read/research-cbd-helps-alzheimers-disease
Research: CBD Helps Alzheimers Disease
By Sirius J · Mon Aug 03, 2015
Past research has implicated CBD in the treatment of Alzheimers disease because of its antioxidant, anti-inflammatory and neuroprotective effects, but due to the irreversible nature of the diseases progression, real breakthroughs are hard to make. For the first time ever, scientists in Australia looked at what long-term oral CBD administration does, and found that it improves social recognition in mice with Alzheimers.
One of the most dramatic and disturbing symptoms of Alzheimers disease is the loss of social recognition; many patients fail to recognize even their own children. Seemingly irreversible changes happen in the brain when a person gets Alzheimers, making treatment of the disease very difficult.
CBD had previously been shown to offer some help as a neural antioxidant in preclinical trials on mice, but without real improvement in their mental state. By using special transgenic mice breed to succumb to the disease, scientists were able to analyze the effects of what preventative CBD treatment does, and the results were impressive. Mice that took 20 mg/kg of CBD (equivalent to almost a gram and a half for someone of average weight) every day before showing symptoms of Alzheimers didnt develop social recognition deficits, even in the middle of full-fledged Alzheimers disease. While some other symptoms were still present, the mice generally had better cognition if they took CBD for long periods of time. The scientists think that this prevention may be linked to CBD-induced retention of dietary phytosterols or neuroinflammatory processes in the brain of mice with the disease.
With daily progress in genomic research, so-called personalized medicine will allow doctors to preventatively treat diseases before they even happen. Mutations on certain chromosomes can whether or not a person is at risk for developing Alzheimers; CBD may one day be used to help these people lead a better life.
http://www.hightimes.com/read/research-cbd-helps-alzheimers-disease
